Dictyostelium discoideum : a Model System for Cell-Cell Interactions in Development
- 8 September 1989
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 245 (4922) , 1054-1058
- https://doi.org/10.1126/science.2672337
Abstract
The cellular slime mold Dictyostelium discoideum undergoes a transition from single-celled amoebae to a multicellular organism as a natural part of its life cycle. A method of cell-cell signaling that controls chemotaxis, morphogenesis, and gene expression has developed in this organism, and a detailed understanding of this signaling system provides clues to mechanisms of intercellular communication in the development of metazoans.Keywords
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