The partitioning ofΔ 1-tetrahydrocannabinol into erythrocyte membranes in vivo and its effect on membrane fluidity1into erythrocyte membranes in vivo and its effect on membrane fluidity1
- 1 August 1984
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 40 (8) , 866-868
- https://doi.org/10.1007/bf01951999
Abstract
Δ 1-Tetrahydrocannabinol (Δ 1-THC) has been quantified directly in erythrocyte membranes from drug-treated mice using gas chromatography/mass spectrometry. Concentrations of approximately 6 ngΔ 1-THC/mg membrane protein (10−5 M) were found when effects of the drug on behavior were prevalent. At these concentrations the drug produced a decrease in membrane order as measured by ESR.Keywords
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