Inhibitors of mitochondrial function prevent senescence in the ascomycetePodospora anserina
- 1 February 1977
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 153 (1) , 111-113
- https://doi.org/10.1007/bf01036003
Abstract
The onset of senescence, i.e. decrease of growth rate followed by cellular death, is prevented when inhibitors of mitochondrial function (ethidiumbromide, streptomycin, tiamulin) are present in the culture medium. If mycelia are transferred to a medium not containing one of these substances, senescence occurs after the usual time interval (30 d at 26° C). Inhibitors of cytoplasmic protein synthesis such as emetine and cycloheximide have no effect in preventing senescence.This publication has 12 references indexed in Scilit:
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