THE NATURE OF GENTAMICIN-INDUCED NEUROMUSCULAR BLOCK
- 1 March 1980
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 52 (3) , 325-326
- https://doi.org/10.1093/bja/52.3.325
Abstract
Gentamicin in concentrations of 0.05–0.2 mmol litre−1 blocked neuromuscular transmission in the toad sartorius nerve-muscle preparation by decreasing the release of transmitter. In concentrations of 0.5–1 mmol litre−1 it decreased the amplitude of the miniature end-plate current by a curare-like action, without affecting the mean open channel lifetime.This publication has 8 references indexed in Scilit:
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