The Identification of Five Rare β-Chain Abnormal Hemoglobins by High Performance Liquid Chromatographic Procedures
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 10 (1) , 49-63
- https://doi.org/10.3109/03630268609072470
Abstract
The detection, quantitation, and characterization of five relatively rare .beta. chain abnormal hemoglobins mainly by high performance liquid chromatographic procedures are described. The variants involved are Hb City of Hope (.beta.69 Gly .fwdarw. Ser), Hb Austin (.beta.40 Arg .fwdarw. Ser), Hb Leiden (.beta.6 or 7 Glu .fwdarw. 0), Hb Louisville (.beta.42 Phe .fwdarw. Leu), and Hb Presbyterian (.beta.108 Asn .fwdarw. Lys). Some clinical and hematological data are also included.This publication has 17 references indexed in Scilit:
- High Performance Liquid Cbromatographic Separation of Globin Chains on a Large-Pore C4ColumnJournal of Liquid Chromatography, 1984
- A Silent Hemoglobin Variant Detected by Hplc: Hemoglobin City of Hope β69 (E13) Gly → SerHemoglobin, 1984
- Separation of tryptic peptides of normal and abnormal a, β, γ, and δ hemoglobin chains by high-performance liquid chromatographyJournal of Chromatography A, 1979
- Micro‐sequence analysis of peptides and proteins using 4‐NN‐dimethylaminoazobenzene 4′‐isothiocyanate/phenylisothiocyanate double coupling methodFEBS Letters, 1978
- Hemoglobins Austin and Waco: Two Hemoglobins with substitutions in the α1β2 contact regionArchives of Biochemistry and Biophysics, 1977
- Hb leiden-β° thalassemia in a chinese with severe hemolytic anemiaAmerican Journal of Hematology, 1977
- Haemoglobin Leiden: Deletion of β6 or 7 Glutamic AcidNature, 1968
- Abnormal human haemoglobins: Separation and characterization of the α and β chains by chromatography, and the determination of two new variants, Hb chesapeake and Hb J (Bangkok)Journal of Molecular Biology, 1966
- A New Haemoglobin in a Thai Family. A Case of Haemoglobin Siriraj- ThalassaemiaBMJ, 1965
- Structural Studies of Aminoethylated Hemoglobins by Automatic Peptide ChromatographyCold Spring Harbor Symposia on Quantitative Biology, 1964