It Takes More Than Two to Nogo
- 16 August 2002
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 297 (5584) , 1132-1134
- https://doi.org/10.1126/science.1076247
Abstract
Growth-inhibitory molecules present in the myelin sheath surrounding CNS neurons prevent the regeneration of injured nerve fibers. In a Perspective, Woolf and Bloechlinger discuss new findings published here (Liu et al.) and elsewhere revealing that three of these growth-inhibitory molecules all bind to the same receptor. This suggests that blocking this receptor may be a good therapeutic approach to promoting neuronal regeneration.Keywords
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