Lipase catalysed Michael addition of secondary amines to acrylonitrile
- 28 June 2004
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 15,p. 1724-1725
- https://doi.org/10.1039/b402244k
Abstract
A new enzymatic process is described. Different preparations of lipase B from Candida antarctica are able to catalyse Michael-type addition of secondary amines to acrylonitrile. This new reaction widens the applicability of these biocatalysts in organic synthesis.Keywords
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