Atrophic arthritis is a constitutional disease which manifests itself as a profound systemic disturbance and by a chronic deforming polyarthritis. It should be clearly understood in the beginning that atrophic arthritis is a disease without a known single specific etiologic agent and likewise there is no single specific cure. In a previous paper one of us1reported carefully controlled experiments with various types of therapy. This consisted of placing a large group of patients with atrophic arthritis on a general program which included dietary correction, bowel management, prevention and correction of deformity, rest, exercise, general physical therapy and climatic residence. After a control period of several months one group had foci of infection removed, another group was given blood transfusions, the third group was given vaccine of various types, and the remainder were given special forms of heliotherapy. Progress was observed over periods ranging form months to years. The results