LDV assessment of methyl nicotinate biological response in aqueous solution against that of a w/o microemulsion system
- 1 December 1994
- journal article
- Published by Wiley in International Journal of Cosmetic Science
- Vol. 16 (6) , 257-264
- https://doi.org/10.1111/j.1467-2494.1994.tb00102.x
Abstract
The aim of this work was to check if the specific microstructure of a water/oil nonionic microemulsion could induce a modification of the bioavailability of a probe (methyl nicotinate). The vasodilatory drug effects were recorded by laser doppler velocimetry in vivo, in man. The results show a quicker activity, and a better release of the drug in the microemulsion, than in the well-known kinetics of an aqueous solution.Keywords
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