Arterial Smooth Muscle Effects of Aldosterone: Action on Ionic Fluxes
- 1 October 1982
- journal article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 63 (s8) , 35s-36s
- https://doi.org/10.1042/cs063035s
Abstract
1. Aldosterone given acutely to male Wistar rats stimulated ouabain-sensitive and ouabain-insensitive 22Na efflux from tail arteries. 2. These effects of aldosterone seem to depend on the activation of specific mineralocorticoid receptors, as they are blocked by antimineralo-corticoid drugs. 3. The results suggest that aldosterone may have a physiological role in the control of vascular tone.Keywords
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