Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man
Open Access
- 1 April 1979
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 39 (4) , 441-444
- https://doi.org/10.1038/bjc.1979.78
Abstract
Serial serum diphenylhydantoin and urinary 5-(p-hydroxphenyl)-5-phenylhydantoin concentrations were determined in 8 patients with malignant disease and 4 healthy volunteers on 2 separate occasions after an oral dose of diphenylhydantoin (500 mg). No significant difference was observed between metabolism before and 10 days after immunization with BCG or Corynebacterium parvum. Volunteers without intervening immunization similarly showed no difference.Keywords
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