Glycosylated haemoglobin in cord blood following normal and diabetic pregnancies

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Abstract
Cord and maternal blood samples were obtained at delivery in 25 normal and 14 diabetic pregnancies (13 insulindependent, one gestational). Total glycosylated haemoglobin, measured by the colorimetric thiobarbiturate method (mmol hydroxymethylfurfural/mol haemoglobin), was lower in cord than maternal blood (mean 18.7±1.7 versus 26.5±2.1, mean ± SD, pr=0.60, pr=0.02, NS). Birth weight ratio was higher in infants of diabetic than of normal mothers (1.10±0.16 versus 0.99±0.13, p< 0.05) but failed to correlate with cord or maternal glycosylated haemoglobin or, in the diabetic group, with mean blood glucose.
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