Antibody against rabbit immunoglobulin VH and L chain allotype determinants in heterologous anti‐lg antisera
- 1 April 1978
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 8 (4) , 253-257
- https://doi.org/10.1002/eji.1830080407
Abstract
Heterologous anti‐rabbit IgG antisera have been examined by radioimmunoassay for the occurrence of anti‐VH antibody. Most of the sera contained antibody specific for VH allotype determinants (Aa1). The antisera contained as much or more anti‐al antibody as estimated in conventional alloantisera. It has further been shown that the anti‐L chain antibody in all these sera was specific for L chain allotype determinants. Antibody against H chain‐dependent L chain conformational determinants or cross‐reacting determinants in CHlγ and CHlα could not be demonstrated.This publication has 25 references indexed in Scilit:
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