Cardiac output determined by the CO2 rebreathing method with correction of lung-bag volume shrinkage.
- 1 January 1984
- journal article
- research article
- Published by Physiological Society of Japan in The Japanese Journal of Physiology
- Vol. 34 (5) , 883-891
- https://doi.org/10.2170/jjphysiol.34.883
Abstract
The purpose of this study [in humans] was to elucidate the effect of lung-bag volume shrinkage on P''.hivin.VCO2 estimated by the CO2 rebreathing method and to correct its effect in calculation of cardiac output. The P''.hivin.VCO2 was extrapolated with the linear relationship between dPACO2/dt and PACO2 during rebreathing. The P''.hivin.VCO2 was higher than real mixed PCO2 by 0.82 mm Hg at rest, by 1.35 mm Hg at 50W, 1.57 mm Hg at 100W and 3.06 mmHg at 150W considering the effect of lung-bag volume shrinkage detected by argon concentration. The cardiac output obtained by the CO2 rebreathing method with correction of these differences was in good agreement with that determined by the acetylene method (r = 0.930, P < 0.001). When the cardiac output was plotted against O2 uptake, results and the regression line were fairly close to the reported regression lines.This publication has 9 references indexed in Scilit:
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