A New Dimension to the Biosynthetic Products Isolated from the SpongeNegombatamagnifica
- 26 May 2004
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 67 (6) , 1055-1057
- https://doi.org/10.1021/np0340753
Abstract
Latrunculeic acid (3), a novel analogue of latrunculin B (2a), was isolated from the Red Sea sponge Negombata magnifica and characterized. Several known compounds were also isolated, including latrunculin B (2a), 15-methoxylatrunculin B (2b), 16-epi-latrunculin B (4), and latrunculin C (5). In contrast to the other members of the latrunculin family, the novel compound 3 is a polyketide devoid of the normal macrocyclic and thiazolidinone rings present in previously identified members of this family.Keywords
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