Effect of Thyroidectomy and Food Intake on Oral and Intravenous Glucose Tolerances in Rats

Abstract
Intravenous studies demonstrated a marked impairment of glucose tolerance in thyroidectomized rats. During the oral test the maximum blood glucose level in the thyroidectomized rats was 50% above that of normals, presumably because of impaired rate of glucose removal from the blood. There was no effect of food intake, or body size, on oral and intravenous glucose tolerance curves in normal and thyroidectomized rats.