Influence of genotype and infantile trauma on adult learning in the mouse.

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Abstract
To study the effects of infantile trauma and hereditary factors upon adult learning in 3 inbred mouse strains, one half the infant Ss in each strain received traumatic auditory stimulation, and one half were reared under standard conditions. Adult learning ability was examined by means of repeated trials in a 4-unit alley maze and in a water escape test. Significant strain differences in maze and water escape learning were observed, and Ss traumatized during infancy were significantly poorer in maze performance than control Ss. There Was also a significant interaction between strain and infantile experience in their effect upon maze learning. There was no evidence for treatment effects or a strain-treatment interaction in the water escape test.

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