The 25 kDa protein kinase inhibitor present in liver cell is absent in fast growing HTC cells and is induced in sodium butyrate treated cells
- 7 October 1985
- journal article
- Published by Wiley in FEBS Letters
- Vol. 190 (1) , 153-156
- https://doi.org/10.1016/0014-5793(85)80447-6
Abstract
We have recently characterized a cAMP independent protein kinase inhibitor in rat liver. This inhibitor is absent or inactive in fast growing HTC cells and is induced according to exponential kinetics by sodium butyrate, a compound which arrests cell growth at the G1 phase of the cell cycle. It is suggested that the inhibitor could be involved in cell growth regulation.Keywords
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