Evaluation of hematoporphyrin photoradiation therapy to treat choroidal melanomas
- 1 January 1984
- journal article
- research article
- Published by Wiley in Lasers in Surgery and Medicine
- Vol. 4 (1) , 59-64
- https://doi.org/10.1002/lsm.1900040108
Abstract
Hematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) was used to treat choroidal melanomas in 23 human subjects. Tumor sizes were divided into three categories: less than 500 mm3 (11 patients), 500‐1,000 mm3 (four patients), and greater than 1,000 mm3 (eight patients). Tumors were exposed to 630 nm laser light at total doses of 300‐3,000 J/cm2. Significant tumor reduction was noted in the subjects with initial tumor volume of less than 500 mm3 and 500‐1,000 mm3.Keywords
This publication has 3 references indexed in Scilit:
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- The mechanism of photodynamic inactivation of human cells in vitro in the presence of haematoporphyrinBritish Journal of Cancer, 1979
- Photoradiation Therapy. II. Cure of Animal Tumors With Hematoporphyrin and Light23JNCI Journal of the National Cancer Institute, 1975