Effects of intermittent haloperidol treatment on dopamine receptor sensitivity in guinea pigs
- 1 September 1984
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 84 (1) , 98-100
- https://doi.org/10.1007/bf00432034
Abstract
Intermittent haloperidol treatment in guinea pigs caused an increase in the behavioral response to apomorphine and an increase in 3H-spiroperidol binding in the striatum to the same degree as continual haloperidol treatment. These results do not support the claim that drug holidays can reduce the incidence of tardive dyskinesia.Keywords
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