Chirality transfer in the cholesterol side chain; synthesis of (24R)- and (24S)-24-hydroxycholesterols

1 January 1982

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 4,p. 258-260
https://doi.org/10.1039/c39820000258

Abstract

Δ²³-22-Acetoxycholesterol derivatives can be converted into 24-hydroxycholestrol derivatives highly stereoselectively by 1,3-chirality transfer with bis(acetaonitrile)palladium(II) dichloride.

Keywords

CHOLESTEROL SIDE
CHIRALITY TRANSFER
HYDROXYCHOLESTROL DERIVATIVES
HIGHLY STEREOSELECTIVELY
ACETOXYCHOLESTEROL DERIVATIVES
HYDROXYCHOLESTEROLS Δ23
DERIVATIVES HIGHLY
SIDE CHAIN