Crush and Smear Technique for Rapid Detection and Semiquantitation of Amyloid Deposition
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in Biotechnic & Histochemistry
- Vol. 66 (4) , 203-207
- https://doi.org/10.3109/10520299109109970
Abstract
A method using Congo red to rapidly identify and semiquantitate amyloid deposits in tissues for experimental research and clinical medicine is described. Examination by polarization microscopy revealed amyloid deposits as bright green birefringent clumps on a dark red background. On semiquantitative evaluation, good correlation was found between this technique and the conventional histological one, the present technique being more sensitive. The method described saves time and expense.Keywords
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