Characterization of an Irritant 4-Deoxyphorbol Diester From Euphorbia Tirucalli
- 1 January 1979
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 42 (1) , 112-115
- https://doi.org/10.1021/np50001a006
Abstract
Latex of E. tirucalli [a horse hold plant whose latex produces Uveitis and kerato conjunctivitis in dog eyes and exhibits tumor-promoting activity on mouse skin] collected in Colombia yielded 12-O-2Z-4E-octadienoyl-4-deoxyphorbol-13-acetate, which exhibited an irritant potency a mouse ear test system. The unsaturated 4-deoxyphorbol diesters recently reported in E. tirucalli grown in South Africa were not observed in the present study.This publication has 4 references indexed in Scilit:
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- Keratoconjunctivitis Resulting From the Sap of Candelebra Cactus and the Pencil TreeArchives of Ophthalmology (1950), 1964
- TUMOR PROMOTION BY EUPHORBIA LATICES1961