Further Studies on SV40-Induced Transformation in Human Renal Cell Cultures. I. Eventual Failure of Subcultivation Despite a Continuing High Rate of Cell Division.
- 1 March 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 115 (3) , 618-621
- https://doi.org/10.3181/00379727-115-28986
Abstract
With a single exception human renal cells transformed by simian virus 40 exhibited eventual failure to undergo serial subcultivation. An increasing rate of aberrant nuclear division was observed concomitantly and may therefore be the immediate factor responsible for the declining growth rate.Keywords
This publication has 5 references indexed in Scilit:
- The serial cultivation of human diploid cell strainsPublished by Elsevier ,2004
- EVIDENCE OF CONTINUOUS TRANSMISSION OF NONINFECTIOUS SV 40 VIRAL GENOME IN MOST OR ALL SV 40 HAMSTER TUMOR CELLSProceedings of the National Academy of Sciences, 1963
- Transformation in hamster kidney monolayers by vacuolating virus, SV-40Virology, 1963
- Induction of Malignancy in vitro in Newborn Hamster Kidney Tissue Infected with Simian Vacuolating Virus (SV40)Experimental Biology and Medicine, 1962
- Multiplication and Cytopathogenicity of Simian Vacuolating Virus 40 in Cultures of Human Tissues.Experimental Biology and Medicine, 1962