On the Constituents of the Fruit of Arctium lappa

Abstract
From the fruits of A. lappa L. (Japanese name goboshi, akujitsu, or dairikishi), 2 new sesquilignan derivatives, AL-D and AL-F, were isolated along with arctin, arctigenin and matairesinol. From spectroscopic and chemical investigations, the structure of AL-D was elucidated as 2-[2-(3-methoxy-4-hydroxy) phenyl-3-hydroxymethyl-7-methoxy-2,3-dihydrobenzofuran-5-yl]methyl-3-(3-methoxy-4-hydroxy)-benzyl-buthyrolactone[I] or 2-(3-methoxy-4-hydroxy) benzyl-3-[2-(3-methoxy-4-hydroxy)-phenyl-3-hydroxymethyl-7-methoxy-2,3-dihydrobenzofuran-5-yl] methyl-buthyrolactone [II]. AL-F was found to be a stereoisomer of AL-D.

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