The Effect of X-Ray Irradiation on the Rat Incisor

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Abstract
Five groups of 30 weanling and 30 adult rats of equal sex distr. were exposed to single, whole-body exposures of 0, 375, 500, 625, and 750 roentgens (r) administered under constant conditions of 250 K.V.; 15 M.A.; Al parabolic filter and 0.5 mm. Cu; H.V.L. 2.1 mm. Cu, and 44 minutes time. Thirty days after exposure, the survivors were sacrificed, the teeth of all animals were examined grossly, and eight animals per group were studied histologically by means of ground and decalcified sections. Data disclosed a slightly greater mortality among males, with no apparent age difference Controls-0; 375r-l (adult female, otitis media); 5000r-6 (3 males); 625-22 (16 males) and 750r-50 (28 males). Gross examination (x 30) revealed increased periodontal disturbances (edematous and bleeding gingivae) and enamel hypoplasia as exposure increased. Histologically, there was temporary retardation or cessation of both enamel and dentin formation, with apparently normal recovery at the formative end of the incisor. At 375r the enamel was affected more than the dentin and was characterized by small, irregular, amorphic, and discolored enamel rods with dark inclusion bodies in the interprismatic substance.

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