AMINO ACID REQUIREMENTS OF HERPES SIMPLEX VIRUS IN HUMAN CELLS

1 March 1964

journal article
research article
Published by American Society for Microbiology in Journal of Bacteriology

Vol. 87 (3) , 609-+
https://doi.org/10.1128/jb.87.3.609-613.1964

Abstract

Progressive infection of human cells minimally infected with herpes simplex virus requires 11 of the amino acids of Eagle''s medium, and glutamine. Lysine is not required, but rather exerts a partially inhibitory effect upon virus multiplication. Infected cells deprived of arginine support neither cytopathogenic effects nor virus replication; when arginine is replaced, a prompt and extensive infection follows. The effect of nutritional deficiencies on virus infection is discussed.

Keywords

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