Marine Natural Products: Pyrrololactams from Several Sponges
- 1 January 1985
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 48 (1) , 47-53
- https://doi.org/10.1021/np50037a008
Abstract
Two pyrrololactams, likely degradation products of more complex known guanidines, were isolated from several marine sponges [Hymeniacidon aldis and lissodendoryx]. 5-Bromo- and 4,5-dibromopyrrole-1-carboxylic acid methyl esters were also isolated. A complex guanidine metabolite, poorly soluble in DMSO [dimethyl sulfoxide], was found to give sharp, resproducible NMR spectra in acid media. [Implications with respect to the cytotoxic properties of these metabolites were presented.This publication has 0 references indexed in Scilit: