Relationship Between Maximum Bicarbonate and Maximum Acid Outputs in the Dog.

Abstract
The maximum bicarbonate output (MBO) of the pancreas in response to secretin and the maximum acid output (MAO) of the stomach in response to histamine were studied in 5 dogs. The MBO represents mEq for mEq, about 30% MAO. Calculations from published human data suggest that the pancreas could neutralize the acid output of a normal stomach.