Plasmodium falciparum takes up iron from transferrin
- 1 October 1984
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 58 (2) , 289-293
- https://doi.org/10.1111/j.1365-2141.1984.tb06087.x
Abstract
Plasmodium falciparum, cultured in vitro, is inhibited by desferrioxamine, a specific iron chelating agent, despite the abundant haem iron which surrounds the parasite. In this report we show that the intraerythrocytic parasite obtains iron from transferrin. The parasite may therefore be freed of a requirement to catabolize haem to obtain iron thus minimizing haem toxicity.Keywords
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