SPECIFICITY OF LACTOFERRIN AS AN INHIBITOR OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING ACTIVITY PRODUCTION FROM FETAL MOUSE-LIVER CELLS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 54  (4) , 951-954
Abstract
Fetal mouse liver cultures capable of producing both erythropoietin and granulocyte-macrophage colony stimulating activity (GM-CSA) were used to study the specificity of lactoferrin as an inhibitor of the production of GM-CSA. Both a granulocyte-derived colony-inhibiting activity and lactoferrin inhibited GM-CSA production with no effect on Ep production. Lactoferrin is specific for GM-CSA production.