NEUTRAL GLYCOLIPID COMPOSITION IN HUMAN CANCER

  • 1 January 1980
    • journal article
    • research article
    • Vol. 5  (1) , 1-6
Abstract
Neutral glycolipid composition of human gastric and colonic cancer was studied in comparison to healthy mucosa. The following compounds were identified: galactosylceramide, glucosylceramide, trihexosylceramide, globoside, small amounts of neotetraosylceramide and fucoglycolipids. The latter comprised 3-0- and 4-0-substituted residues of N-acetylglucosamine. In cancer tissue the contents of lactosylceramide and of fucoglycolipids were increased. Fatty acid compositions of neutral glycolipids derived from cancer and control samples were similar. The most abundant fatty acids were palmitic and nervonic acids.