Caution in interpretation needed
- 11 March 1995
- Vol. 310 (6980) , 667
- https://doi.org/10.1136/bmj.310.6980.667
Abstract
EDITOR,—Considerable caution must be exercised in interpreting the results of Lyn March and colleagues' n of 1 trials in osteoarthritis.1 For example, the authors observe that “seven of he eight patients who changed treatment from baseline changed to paracetamol (P=0.07, exact binomial).” Of the 20 patients analysed, 16 were taking a non-steroidal anti-inflammatory drug and only three were taking paracetamol. Therefore, at most three patients could have changed their treatment from paracetamol. Furthermore, the authors implicitly assume that failure to find …Keywords
This publication has 2 references indexed in Scilit:
- n of 1 trials comparing a non-steroidal anti-inflammatory drug with paracetamol in osteoarthritisBMJ, 1994
- Suspended judgment n-of-1 trialsControlled Clinical Trials, 1993