External irradiation for malignant thyroid tumors.

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Abstract
Thirty-eight patients with residual or recurrent primary thyroid cancers which did not take up 131I were treated with external beam irradiation. Excluding 5 patients with malignant lymphoma, there were 23 patients with local disease and 10 with distant metastases. Doses ranged from 3500-7000 rad among the 23 with local disease; local tumor control was achieved in 8. Six are alive and well 2-11 yr later. External beam irradiation should be considered in locally advanced, incompletely resected, recurrent and metastatic thyroid malignancies of all histological types without 131I uptake. Reviewed are the age and sex distribution, histology, stage, extent of surgery, and dose and radiotherapy technique as they affect survival and patterns of failure.

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