Fatty acid analysis of lipid components of livers from dairy cows with high levels of serum free fatty acids.
- 1 January 1988
- journal article
- research article
- Published by Japanese Society of Veterinary Science in The Japanese Journal of Veterinary Science
- Vol. 50 (4) , 900-907
- https://doi.org/10.1292/jvms1939.50.900
Abstract
Thirteen slaughtered dairy cows with high serum fatty acid levels (902 to 2127 .mu.Eq/l) were examined for their liver lipid components and the fatty acid composition of each component. Almost all of the cows showed parturient paresis or ketosis and had fatty degeneration or hydropic degeneration in their livers. In the diseased livers, the levels of triglyceride increased and those of cholesterol ester, phosphatidyl ethanolamine, and sphingomyelin decreased compared with those from five healthy cows. The unsaturated fatty acid components C18-1 and C18-2 in cholesterol ester and free fatty acids increased, and C18 saturated fatty acid of these lipid components decreased. Polyenoic acids such as C20-3, C20-4 and C22-4, which become precursors of chemical and physiological mediators such as prostaglandins, thromboxanes and leukotrienes, dramatically decreased in all phospholipid component except sphingomyelin. In this paper, the question of whether the lack of such polyenoic acid synthesis in liver may cause a clinical sign of parturient paresis in daily cows is discussed.This publication has 0 references indexed in Scilit: