FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes
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Open Access
- 22 January 2004
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 20 (4) , 578-580
- https://doi.org/10.1093/bioinformatics/btg455
Abstract
Summary: We present a simple but powerful procedure to extract Gene Ontology (GO) terms that are significantly over- or under-represented in sets of genes within the context of a genome-scale experiment (DNA microarray, proteomics, etc.). Said procedure has been implemented as a web application, FatiGO, allowing for easy and interactive querying. FatiGO, which takes the multiple-testing nature of statistical contrast into account, currently includes GO associations for diverse organisms (human, mouse, fly, worm and yeast) and the TrEMBL/Swissprot GOAnnotations@EBI correspondences from the European Bioinformatics Institute. Availability:http://fatigo.bioinfo.cnio.esKeywords
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