Antitumor Agents, 82. Cytotoxic Sapogenols from Aesculus hippocastanum
- 1 July 1986
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 49 (4) , 650-656
- https://doi.org/10.1021/np50046a015
Abstract
Two cytotoxic sapogenols, the new hippocaesculin (1) and the known barringtogenol-C 21-angelate (2), were isolated from the acid hydrolysis product of a crude saponin fraction that was obtained from the fruits of Aesculus hippocastanum. The structures of 1 and 2 were determined from their chemical transformations and spectral data. Compound 1 is either 21-O-angeloyl, 22-O-tigloyl R1-barrigenol, or 21-O-tigloyl, 22-O-angeloyl R1-barrigenol.This publication has 2 references indexed in Scilit:
- Studies on the constituents of Xanthoceras sorbifolia Bunge. II. Major sapogenol and a prosapogenin from the fruits of Xanthoceras sorbifolia Bunge.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
- Über die protoäscigeninester aus äscinTetrahedron, 1966