PATHOLOGIC FEATURES OF HORSES GIVEN AVIRULENT EQUINE ARTERITIS VIRUS INTRAMUSCULARLY

  • 1 January 1981
    • journal article
    • research article
    • Vol. 42  (7) , 1218-1220
Abstract
Twenty horses that were seronegative for equine arteritis virus antibodies were inoculated i.m. with live equine arteritis virus vaccine. The inoculation did not cause clinical signs of disease. A mild, transient febrile reaction developed in 6 horses, 3 of which were in poor condition before inoculation. Six horses, 2 of which were in poor condition before inoculation, experienced mild lymphopenia. Necropsy revealed mild lesions in the lymph nodes of 6 horses (3 of which were in poor condition before inoculation). Maximum concentrations of virus were detected in the lymph nodes and were consistently present from postvaccination day 3-8. Lesser concentrations of virus were detected in the spleen of 5 horses, liver and kidney of 4, abdominal fluid of 3, pleural fluid of 2 and lungs and urine of 1, between postvaccination days 3-7. Virus was not detected in the brain, nasal tract or serum of any of the horses.

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