Presence of a Covalently Linked Protein on Calicivirus RNA
- 1 November 1978
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 41 (2) , 443-446
- https://doi.org/10.1099/0022-1317-41-2-443
Abstract
Summary The infective RNA of the calicivirus, vesicular exanthema virus, has been shown to contain a protein which is apparently linked to the RNA by a covalent bond. The protein remained bound to the RNA after boiling with SDS-mercaptoethanol-urea or treating with formamide-dimethylsulphoxide but was removed by incubating with proteinase K. The mol. wt. of the protein was estimated to be about 10 × 103 by electrophoresis in highly cross-linked polyacrylamide gels. The infectivity of the RNA was destroyed by removal of the protein with proteinase K.This publication has 8 references indexed in Scilit:
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