UTERINE T-MYCOPLASMA COLONIZATION IN REPRODUCTIVE FAILURE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 130  (3) , 307-311
Abstract
In 46 patients with a history of habitual abortion and in 18 women with primary unexplained infertility, samples from cervical mucus and endometrial tissue were examined for presence of T-mycoplasma and the results compared to those obtained among 45 control subjects. Colonization of T-mycoplasma in the cervix was common in all patient groups (49-83%), wheras colonization in the endometrium was significantly more frequent among the habitual abortion patients (28%) and the infertility patients (50%) than among the control sujects (7%). In all patients having T-mycoplasma-positive endometria the organism was also isolated from the cervix, having T-mycoplasma-positive endometria the organism was also isolated from the cervix, indicating an ascending route for the colonization of the uterine cavity. Bacteria belonging to the normal vaginal flora were frequently co-isolated from the endometrial samples along with T-mycoplasma. The women with T-mycoplasma-positive endometria showed a high incidence of postabortion fever. Treatment with doxycycline eradicated T-mycoplasma from the cervix and the endometrium and apparently led to an improvement with respect to the outcome of the posttreatment pregnancies.

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