SOS Regulation of qnrB Expression
- 1 February 2009
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 53 (2) , 821-823
- https://doi.org/10.1128/aac.00132-08
Abstract
In the sequence upstream from qnrB (but not qnrA or qnrS) is a LexA binding site. qnrB was shown to be under SOS control by demonstrating that quinolone susceptibility decreased with increasing temperature in a strain with a recA441(Ts) allele, whereas qnrB expression increased in response to ciprofloxacin or mitomycin C in strains with an intact lexA gene.Keywords
This publication has 30 references indexed in Scilit:
- qnr Gene NomenclatureAntimicrobial Agents and Chemotherapy, 2008
- Qnr-like pentapeptide repeat proteins in Gram-positive bacteriaJournal of Antimicrobial Chemotherapy, 2008
- Role of a qnr -Like Gene in the Intrinsic Resistance of Enterococcus faecalis to FluoroquinolonesAntimicrobial Agents and Chemotherapy, 2007
- Vibrio splendidus as the Source of Plasmid-Mediated QnrS-Like Quinolone Resistance DeterminantsAntimicrobial Agents and Chemotherapy, 2007
- The worldwide emergence of plasmid-mediated quinolone resistanceThe Lancet Infectious Diseases, 2006
- qnr Prevalence in Ceftazidime-Resistant Enterobacteriaceae Isolates from the United StatesAntimicrobial Agents and Chemotherapy, 2006
- Lethal fragmentation of bacterial chromosomes mediated by DNA gyrase and quinolonesMolecular Microbiology, 2006
- qnrB , Another Plasmid-Mediated Gene for Quinolone ResistanceAntimicrobial Agents and Chemotherapy, 2006
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001
- Induction of SOS genes in Escherichia coli and mutagenesis in Salmonella typhimurium by fluoroquinolonesMutagenesis, 1990