Early stopping of randomized clinical trials for overt efficacy is problematic
- 31 March 2008
- journal article
- review article
- Published by Elsevier in Journal of Clinical Epidemiology
- Vol. 61 (3) , 241-246
- https://doi.org/10.1016/j.jclinepi.2007.07.016
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- A Randomized, Double‐Blind, Placebo‐Controlled Trial of Combined Nevirapine and Zidovudine Compared with Nevirapine Alone in the Prevention of Perinatal Transmission of HIV in ZimbabweClinical Infectious Diseases, 2007
- Current controversies in data monitoring for clinical trialsClinical Trials, 2006
- Celecoxib Versus Placebo for Men With Prostate Cancer and a Rising Serum Prostate-Specific Antigen After Radical Prostatectomy and/or Radiation TherapyJournal of Clinical Oncology, 2006
- Randomized, Controlled Intervention Trial of Male Circumcision for Reduction of HIV Infection Risk: The ANRS 1265 TrialPLoS Medicine, 2005
- Pretreatment cortisol values may predict responses to hydrocortisone administration for the prevention of bronchopulmonary dysplasia in high-risk infantsThe Journal of Pediatrics, 2005
- Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over timeJournal of Clinical Epidemiology, 2004
- Are the recommendations to use perioperative -blocker therapy in patients undergoing noncardiac surgery based on reliable evidence?CMAJ : Canadian Medical Association Journal, 2004
- The Effect of Bisoprolol on Perioperative Mortality and Myocardial Infarction in High-Risk Patients Undergoing Vascular SurgeryNew England Journal of Medicine, 1999
- Practical problems in interim analyses, with particular regard to estimationControlled Clinical Trials, 1989
- Equipoise and the Ethics of Clinical ResearchNew England Journal of Medicine, 1987