SERUM CONCENTRATIONS OF RADIOIODINE IN DIAGNOSTIC TRACER STUDIES*

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Abstract
IN RECENT years radioactive iodine, I131, has been utilized widely in the diagnosis and study of thyroid disease (1). In spite of this, relatively little attention has been given to the measurement of serum radioiodine concentrations in patients receiving tracer amounts of I131 for routine diagnostic studies; particularly is this true of the study of serum I131 concentrations at periods of four days and longer following the administration of radioiodine. Recently Silver and Fieber (2) have described the results of such measurements and their usefulness in the diagnosis of hyperthyroidism. The present work provides confirmation of the results of these authors and further extends the application of this procedure in the study of thyroid metabolism. Tracer studies for determination of thyroid status are carried out routinely by the Radioisotope Laboratory at the request of the various clinical services of the hospital.