Abstract
Financial constraints in health care in general and critical care services in particular have placed increasing demands upon health care professionals and decision-makers to ensure the highest quality of care with the best possible outcomes are attained for the least possible expenditure of resources. As such, pharmacoeconomic methods have become increasingly applied to pressing clinical problems to facilitate cost-effective delivery of health care services to the critically ill. This manuscript briefly details the basic tenets of pharmaco-economic analysis and provides an overview of recent applications to critical care issues.