A new rapid method for quantification of nitrogen in human serum employing the14N(p, p'γ)14N reaction: application to human pregnancy
- 1 September 1985
- journal article
- research article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 30 (9) , 921-928
- https://doi.org/10.1088/0031-9155/30/9/004
Abstract
The total nitrogen concentrations in dried from 54 pregnant women and 17 newborn babies were determined by a new applications of the 14N(p, p' gamma )14N reaction resonance at 3.9 MeV. The samples were bombarded in a He atmosphere by 4.1 MeV protons from a tandem Van de Graaf accelerator. The mean dry-weight nitrogen concentration in serum sampled during early pregnancy (6-12 weeks; 13.9 g per 100 g+or-5.4%) was significantly higher than that in serum sampled during later pregnancy (38-42 weeks: 13.0 g per 100 g+or-3.9%, p<0.001) and than that in serum taken from the umbilical cord (13.3 g per 100 g+or-4.6%, p<0.01). The nitrogen levels measured using this rapid nuclear technique, applied for the first time to human serum analysis, agree well with parallel Kjeldahl analyses.Keywords
This publication has 11 references indexed in Scilit:
- Nitrogen determination with external beam proton induced gamma-ra emission analysisNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1984
- Selenium and other elements in human maternal and umbilical serum, as determined simultaneously by proton-induced X-ray emission.Clinical Chemistry, 1984
- An external proton beam for PIGE analysisNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 1984
- Proton-induced prompt gamma-ray emission for determination of light elements in human boneJournal of Radioanalytical and Nuclear Chemistry, 1981
- Energy levels of light nuclei A = 13–15Nuclear Physics A, 1981
- Proton-induced thick-target gamma-ray yields for the elemental analysis of the Z=3–9, 11–21 elementsJournal of Radioanalytical and Nuclear Chemistry, 1981
- Clinical Chemistry of PregnancyPublished by Elsevier ,1980
- Prompt gamma neutron activation analysis to measure whole body nitrogen absolutely: Its application to studies of in-vivo changes in body composition in health and diseaseJournal of Radioanalytical and Nuclear Chemistry, 1977
- A New Time-Saving Method for Determining Nitrogen in Biologic MaterialClinical Chemistry, 1968