pT(1) Bladder Cancer
- 1 January 1991
- journal article
- review article
- Published by Elsevier in European Urology
- Vol. 20 (1) , 1-8
- https://doi.org/10.1159/000471649
Abstract
PT(1) bladder tumors invade the lamina propria and are more agressive biologically than superficial pTa or in situ carcinomas (Tis). Among patients with pT(1) tumors treated by transurethral resection (TUR), 30% develop a muscle-invasive neoplasm within 3-5 years, but intravesical chemotherapy or BCG reduce progression rates to 20 and 14%, respectively. Tumor variables favoring progression include multiple, recurrent pT! tumors, high grade (G3), solid configuration and associated Tis. Many pT(1) tumors can be managed conservatively, but patients failing an adequate trial (3-6 months) of TUR and intravesical therapy are best treated by cystectomy.Keywords
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