Prokaryotic genetic code
- 1 December 1990
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 46 (11-12) , 1097-1106
- https://doi.org/10.1007/bf01936919
Abstract
The prokaryotic genetic code has been influenced by directional mutation pressure (GC/AT pressure) that has been exerted on the entire genome. This pressure affects the synonymous codon choice, the amino acid composition of proteins and tRNA anticodons. Unassigned codons would have been produced in bacteria with extremely high GC or AT genomes by deleting certain codons and the corresponding tRNAs. A high AT pressure together with genomic economization led to a change in assignment of the UGA codon, from stop to tryptophan, inMycoplasma.Keywords
This publication has 33 references indexed in Scilit:
- Codon—anticodon pairing: The wobble hypothesisPublished by Elsevier ,2009
- Codon recognition patterns as deduced from sequences of the complete set of transfer RNA species in Mycoplasma capricolum: Resemblance to mitochondriaPublished by Elsevier ,2004
- Genomic organization and physical mapping of the transfer RNA genes in Escherichia coli K12Journal of Molecular Biology, 1990
- MOLECULAR AND CELLULAR BIOLOGY OF SPIROPLASMASPublished by Elsevier ,1989
- A novel lysine-substituted nucleoside in the first position of the anticodon of minor isoleucine tRNA from Escherichia coliPure and Applied Chemistry, 1989
- Evolution of the genetic code as affected by anticodon contentTrends in Genetics, 1988
- Evolutionary dynamics of tryptophan tRNAs in Mycoplasma capricolumMolecular Genetics and Genomics, 1988
- Compositional constraints and genome evolutionJournal of Molecular Evolution, 1986
- Silent nucleotide substitutions and G+C content of some mitochondrial and bacterial genesJournal of Molecular Evolution, 1986
- Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genesJournal of Molecular Biology, 1981