Activation of Serum Lactic Dehydrogenase

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Abstract
THREE lactic acid dehydrogenase (LDH) isozyme patterns are known to be associated with increased serum LDH activities1 (Fig. 1). One common pattern, called the alpha LDH abnormality, is associated with erythrocyte hemolysis and with injuries of the renal cortex and myocardium. A second common pattern, called the beta-gamma LDH abnormality, is associated with injuries of the liver, skeletal muscle and skin. A much less common pattern, called the isomorphic LDH abnormality, is associated with some types of proliferative and disseminated neoplastic diseases. The alpha and beta-gamma LDH abnormalities precisely reflect the LDH isozyme patterns found in the . . .