Cyclophosphamide modulates CD4+ T cells into a T helper type 2 phenotype and reverses increased IFN-γ production of CD8+ T cells in secondary progressive multiple sclerosis
- 1 January 2004
- journal article
- research article
- Published by Elsevier in Journal of Neuroimmunology
- Vol. 146 (1-2) , 189-198
- https://doi.org/10.1016/j.jneuroim.2003.10.036
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1Proceedings of the National Academy of Sciences, 2000
- CCR5+and CXCR3+T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesionsProceedings of the National Academy of Sciences, 1999
- Elevated interleukin-12 in progressive multiple sclerosis correlates with disease activity and is normalized by pulse cyclophosphamide therapy.Journal of Clinical Investigation, 1998
- Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2sThe Journal of Experimental Medicine, 1998
- Mechanisms of interferon beta action in multiple sclerosisMultiple Sclerosis Journal, 1997
- Interferon beta results in immediate reduction of contrast‐enhanced MRI lesions in multiple sclerosis patients followed by weekly MRINeurology, 1997
- Human Chemokines: An UpdateAnnual Review of Immunology, 1997
- Interferon-gamma-secreting cells in multiple sclerosis patients treated with interferon beta-1bNeurology, 1995
- Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: Do cytokines trigger off exacerbations?Acta Neurologica Scandinavica, 1988
- The effect of cyclophosphamide on T lymphocytes and T lymphocyte subsets in patients with chronic progressive multiple sclerosisActa Neurologica Scandinavica, 1984