High-Resolution Field Desorption/Ionization Fourier Transform Ion Cyclotron Resonance Mass Analysis of Nonpolar Molecules
- 1 April 2003
- journal article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 75 (9) , 2172-2176
- https://doi.org/10.1021/ac020627v
Abstract
We report the first field desorption ionization broadband high-resolution (m/Δm50% ≈ 65 000) mass spectra. We have interfaced a field ionization/field desorption source to a home-built 9.4-T FT-ICR mass spectrometer. The instrumental configuration employs convenient sample introduction (in-source liquid injection) and external ion accumulation. We demonstrate the utility of this configuration by generating high-resolution positive-ion mass spectra of C60 and a midboiling crude oil distillate. The latter contains species not accessible by common soft-ionization methods, for example, low-voltage electron ionization, electrospray ionization, and matrix-assisted laser desorption/ionization. The present work demonstrates significant advantages of FI/FD FT-ICR MS for analysis of nonpolar molecules in complex mixtures.Keywords
This publication has 25 references indexed in Scilit:
- Field desorption mass spectrometry of large multiply branched saturated HydrocarbonsJournal of Mass Spectrometry, 2001
- Molecular characterization of petroporphyrins in crude oil by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometryCanadian Journal of Chemistry, 2001
- A Null Lesion in the Rhodopin 3,4-Desaturase of Rhodospirillum rubrum Unmasks a Cryptic Branch of the Carotenoid Biosynthetic PathwayBiochemistry, 1998
- Analysis of ruthenium carbonyl–porphyrin complexes: a comparison of matrix-assisted laser desorption/ionisation time-of-flight, fast-atom bombardment and field desorption mass spectrometryEuropean Journal of Mass Spectrometry, 1997
- Mass spectrometry of underivatized naturally occurring glycosidesPhytochemical Analysis, 1992
- Protonated moleclar species of phosphtidylserines by field desorption mass spectrometryJournal of Mass Spectrometry, 1991
- Electron ionization mass spectrometry of synthetic C60Rapid Communications in Mass Spectrometry, 1990
- Electrospray ionization with Fourier‐transform mass spectrometry. Charge state assignment from resolved isotopic peaksJournal of Mass Spectrometry, 1990
- Evaluations of heavy constituents in fractions of petroleum residues using gel permeation and field desorption mass spectrometryAnalytical Chemistry, 1986
- Theory of Fourier transform ion cyclotron resonance mass spectroscopy: Response to frequency-sweep excitationThe Journal of Chemical Physics, 1980